Mariano Diaz has tested positive for COVID-19 and will miss the Champions League clash against Manchester City.
The 26-year-old will not feature against Man City in next month’s Round of 16 second leg tie.
He has also entered a period of self-isolation and quarantine.
Mariano hasn’t started a single game this season and has made just four substitute appearances for Real Madrid.
Man City vs. Real Madrid could now be in serious doubt following the positive COVID-19 not to mention Spain’s recent wave of coronavirus, which has seen the country placed on UK’s quarantine list.
But Madrid have been made exempt from strict rules preventing travellers from Spain coming here without a fortnight’s quarantine.
Though news that there is a positive result within the Spanish side’s camp could prevent the second leg from happening.
The Champions League fixture is currently scheduled for August 7 at the Etihad with Man City leading Real Madrid following their 2-1 victory in February.